What it is used for
- Reducing stroke risk in people with atrial fibrillation
- Treating and preventing blood clots in the legs (DVT) and lungs (PE)
- Preventing clots after some hip or knee operations
How it works
Apixaban blocks factor Xa, an essential step in clot formation, making the blood less likely to form harmful clots. It works quickly and usually does not require routine blood-test monitoring.
How it is taken
Usually supplied as oral tablets, typically taken twice a day with or without food. Take it exactly as your doctor or pharmacist directs and as written on the label, and do not stop suddenly without medical advice.
No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.
Common side effects
- Easy bruising
- Nosebleeds or bleeding gums
- Heavier periods
- Mild nausea
- Anaemia (low blood count) noted on tests
Serious effects — get help
- Heavy or uncontrolled bleeding, blood in urine or stools, black/tarry stools, vomiting or coughing up blood - seek urgent care
- Sudden severe headache, weakness, confusion or vision change (possible brain bleed) - emergency
- Serious fall or head injury while taking it - get checked promptly
- Serious allergic reaction: facial or throat swelling, trouble breathing
If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.
Interactions to watch
- Other blood thinners and aspirin
- Anti-inflammatory painkillers (NSAIDs)
- Certain antifungal and HIV medicines
- Some seizure medicines and rifampicin
- St John's Wort
- Alcohol in excess
Who should take care
- Generally avoided in pregnancy and breastfeeding - tell your clinician if this applies
- Report any kidney or liver problems
- Tell any doctor, dentist or surgeon that you take it before procedures
- Do not stop abruptly, as clot risk can rise
- Carry an anticoagulant alert card if given one