What it is used for
- Inflammatory conditions such as severe arthritis flares and inflammatory bowel disease
- Asthma and other allergic or breathing conditions
- Autoimmune diseases
- Severe allergic reactions and some skin, eye and other inflammatory disorders
How it works
Prednisolone is a corticosteroid that calms inflammation and dampens an overactive immune system across the body, reducing swelling, redness, pain and allergic or autoimmune activity.
How it is taken
Available as tablets, soluble/dispersible tablets, oral solution, and as eye drops and other specialist forms. Take it exactly as your doctor or the label directs, usually with or after food, and often in the morning. Do not stop it suddenly after more than a short course — your doctor will tell you how to reduce it gradually.
No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.
Common side effects
- Increased appetite and weight gain
- Indigestion
- Difficulty sleeping or mood changes
- Raised blood sugar and fluid retention
Serious effects — get help
- Signs of serious infection (steroids can mask or worsen infections)
- Severe mood changes, confusion or psychosis
- Stomach ulcer or bleeding
- Symptoms of adrenal crisis if stopped abruptly (severe fatigue, dizziness, low blood pressure)
- Vision changes, severe abdominal pain, or signs of high blood sugar
If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.
Interactions to watch
- NSAIDs (increased stomach-bleeding risk)
- Some diabetes medicines (steroids raise blood sugar)
- Live vaccines (generally avoided during treatment)
- Medicines affecting potassium and blood pressure
- Some medicines that change how the steroid is processed
Who should take care
- Do not stop suddenly after prolonged use — this can be dangerous; follow a tapering plan
- Carry a steroid card and tell any healthcare professional you are taking it
- Tell your doctor about diabetes, high blood pressure, infections, stomach ulcers, glaucoma or bone thinning
- Avoid contact with chickenpox or measles if you have not had them, as infections can be severe
- Seek urgent care for signs of serious infection or adrenal crisis