What it is used for
- Fungal nail infections (onychomycosis)
- Skin fungal infections including ringworm and pityriasis versicolor
- Oral and vaginal thrush
- Some deeper or systemic fungal infections (such as aspergillosis) under specialist care
How it works
Itraconazole blocks an enzyme fungi use to make ergosterol, an essential part of their cell membrane. Without it the fungal cell membrane breaks down and the fungus is killed, clearing the infection.
How it is taken
Comes as capsules and an oral liquid/solution; the two forms are absorbed differently and are not always interchangeable. Capsules are usually taken with food, while the liquid is often taken on an empty stomach. Take it exactly as your doctor, pharmacist, or label directs and complete the full course, which can be lengthy for nail infections.
No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.
Common side effects
- Nausea
- Stomach upset
- Diarrhoea
- Headache
- Rash
- Dizziness
Serious effects — get help
- Signs of liver problems (yellowing skin or eyes, dark urine, severe tiredness)
- Signs of heart failure such as breathlessness, swollen ankles, or sudden weight gain
- Severe skin reactions
- Numbness or tingling in hands or feet
- Severe allergic reaction
If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.
Interactions to watch
- Many medicines, including some statins, sedatives, and heart-rhythm drugs, can be dangerous with itraconazole
- Antacids and acid-reducing medicines can reduce absorption of the capsules
- Tell your clinician about every medicine, including over-the-counter products
Who should take care
- Not recommended for people with certain heart conditions such as heart failure
- Tell your doctor about liver problems; liver monitoring may be needed
- Use in pregnancy is generally avoided unless essential
- Mention any previous reaction to antifungal medicines