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Progestogen (synthetic progesterone-like hormone)

Dydrogesterone: uses, side effects & precautions

Also known as Duphaston, dydrogesterone.

Queste informazioni hanno carattere puramente orientativo e non costituiscono un parere medico. Consulta sempre un professionista sanitario qualificato per problemi medici personali. In caso di emergenza, chiama il numero di emergenza locale.

What it is used for

  • Irregular, absent, or heavy periods linked to low progesterone
  • Painful periods and some menstrual disorders
  • Supporting the womb lining as part of certain hormone therapy or fertility treatment (when prescribed)
  • Some pregnancy-support uses under specialist care

How it works

It acts like the body's own progesterone on the womb lining, helping to regulate the menstrual cycle and support the lining when natural progesterone is low.

How it is taken

Taken as a tablet on a schedule that depends on the reason for use, such as during part of the menstrual cycle. Take it exactly as your doctor directs, as timing within the cycle matters.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Headache
  • Nausea
  • Breast tenderness
  • Changes in bleeding pattern
  • Mood changes
  • Tiredness

Serious effects — get help

  • Signs of a serious allergic reaction
  • Yellowing of the skin or eyes
  • Unexpected heavy or unusual vaginal bleeding
  • Symptoms suggesting a blood clot (uncommon)

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Liver-enzyme-inducing medicines (some epilepsy and TB drugs, St John's Wort)
  • Tell your clinician about all medicines

Who should take care

  • Tell your clinician about any unexplained vaginal bleeding, liver disease, or hormone-sensitive cancer before use
  • Take it according to the correct days of your cycle as instructed
  • Report any unexpected or heavy bleeding
  • Tell your clinician if you are or might be pregnant, as the plan depends on your situation

Frequently asked questions

What is it used for?
It is a progestogen used to help regulate periods, treat some menstrual problems, and support the womb lining in certain hormone or fertility treatments.
When in the cycle do I take it?
Often during a specific part of the cycle, depending on the reason. Follow the exact schedule your clinician gives you.
Is it a contraceptive?
It is not used as a standalone contraceptive at these doses, so do not rely on it to prevent pregnancy unless your clinician says so.
Can it cause a period?
When used to treat absent or irregular periods, a bleed often follows the course. Your clinician will explain what to expect.
Is Dydrogesterone safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

Related conditions

Related medicines

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