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Antihistamine plus decongestant (ophthalmic)

Antazoline with xylometazoline: uses, side effects & precautions

Also known as Otrivine-Antistin.

Queste informazioni hanno carattere puramente orientativo e non costituiscono un parere medico. Consulta sempre un professionista sanitario qualificato per problemi medici personali. In caso di emergenza, chiama il numero di emergenza locale.

What it is used for

  • Allergic conjunctivitis with redness
  • Itchy, red, watery eyes from hay fever and other allergies

How it works

Antazoline is an antihistamine that calms allergic itching and watering, while xylometazoline narrows surface eye blood vessels to reduce redness. Together they relieve both the itch and the redness of an allergic eye reaction.

How it is taken

Comes as eye drops, available over the counter in some regions. A drop is placed into the affected eye(s). Wash your hands first and keep the dropper tip clean. Use only for short periods exactly as the label or pharmacist directs, because the decongestant part can cause rebound redness with overuse.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Brief stinging or burning on application
  • Temporary blurred vision
  • Dry eyes
  • Dilated pupils
  • Rebound redness with overuse

Serious effects — get help

  • Eye pain, persistent redness or vision changes
  • Signs of an allergic reaction such as facial swelling, rash or breathing difficulty
  • Fast or irregular heartbeat or dizziness

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Other eye drops (space them apart; ask a pharmacist)
  • Certain blood pressure, heart or antidepressant medicines (tell your clinician)
  • Contact lenses (avoid wearing during use unless advised)

Who should take care

  • Do not use long term because of rebound redness
  • Avoid in glaucoma or certain eye conditions unless approved by a clinician
  • Tell a pharmacist about heart, thyroid or blood pressure problems
  • Keep out of reach of children
  • Tell your clinician if pregnant or breastfeeding

Frequently asked questions

How is this different from a plain antihistamine eye drop?
It adds a decongestant to reduce redness as well as itch, but that decongestant means it should only be used short term.
Why can't I use it for weeks?
The decongestant part can cause rebound redness with prolonged use. For ongoing allergy, a pharmacist may suggest a different long-term drop.
Can I wear contacts with it?
Generally avoid lenses while using it unless told otherwise. Ask a pharmacist about timing.
Is it safe if I have high blood pressure?
Tell your clinician or pharmacist first, as the decongestant can affect blood pressure and heart rhythm.

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