Common pain and fever relievers such as paracetamol and ibuprofen do not interact with most antibiotics and can help you feel more comfortable while the antibiotic treats the infection. Take them as directed on the packaging.
There are a few situations to be careful with, for example if you have kidney problems, stomach ulcers, or asthma affected by ibuprofen, or if you take other medicines that overlap. Some specific antibiotics have particular interactions, so it is worth a quick check.
Ask your pharmacist if you are unsure, especially if you take several medicines. Do not exceed the recommended amounts of any painkiller, and avoid taking two products containing the same ingredient at once.