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Antibiotic (third-generation cephalosporin, injectable)

Ceftriaxone: uses, side effects & precautions

Also known as Rocephin.

Ces informations sont fournies à titre indicatif uniquement et ne constituent pas un avis médical. Consultez toujours un professionnel de santé qualifié pour toute préoccupation médicale personnelle. En cas d'urgence, appelez votre numéro d'urgence local.

What it is used for

  • Serious chest infections such as some pneumonia
  • Severe urinary and kidney infections
  • Certain meningitis
  • Some sexually transmitted infections such as gonorrhoea
  • Serious skin, bone and abdominal infections
  • Infections needing hospital treatment

How it works

Ceftriaxone is a cephalosporin antibiotic given by injection or drip. It blocks bacteria from building their cell walls so they break down and die. It is used for more serious infections, often in hospital or a clinic.

How it is taken

Given as an injection into a muscle or as a drip into a vein, usually by a healthcare professional in a hospital or clinic. It is used exactly as directed by the medical team. There is no standard over-the-counter version; the dosing and schedule are managed by your clinicians.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Pain or hardness where the injection was given
  • Diarrhoea
  • Nausea
  • Rash
  • Changes in some blood test results

Serious effects — get help

  • Severe allergic reaction with swelling or breathing difficulty
  • Severe, persistent or bloody diarrhoea
  • Yellowing of the skin or eyes
  • Severe blistering skin reactions
  • Pain in the right upper abdomen (rare gallbladder sludge or stones)

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Calcium-containing fluids or supplements given into a vein (especially in newborns)
  • Blood thinners such as warfarin
  • Some other antibiotics
  • Certain vaccines

Who should take care

  • Tell the medical team about any penicillin or cephalosporin allergy
  • Tell them if you have kidney or liver problems or gallbladder problems
  • Special care is needed in newborn babies
  • Discuss pregnancy or breastfeeding with the medical team
  • Mention all other medicines you take

Frequently asked questions

Why is ceftriaxone given by injection?
It is not well absorbed as a tablet, so it is given by injection or a drip, usually for more serious infections that need reliable, strong treatment.
Can I take it at home?
It is normally given by a healthcare professional in a hospital or clinic. Some services arrange supervised injections; follow your care team's instructions.
Is it used for gonorrhoea?
It is one of the main antibiotics used for gonorrhoea. Your clinician will also advise on testing and partner treatment.
Is it safe in pregnancy?
It is often used when needed in pregnancy, but your care team will weigh the benefits and risks for you.

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