What it is used for
- Respiratory and chest infections
- Sinus and ear infections that have not responded to other antibiotics
- Some urinary tract infections
- Skin and soft-tissue infections
- Dental infections
- Animal or human bite infections
How it works
This medicine combines amoxicillin (a penicillin antibiotic) with clavulanic acid. Clavulanic acid blocks an enzyme that some bacteria use to defend themselves against penicillins, so the combination can work against bacteria that plain amoxicillin cannot.
How it is taken
Comes as tablets and a liquid (oral suspension), and as an injection in hospital. Take it exactly as your doctor or pharmacist directs and follow the label. Taking it with or just before food can reduce stomach upset. Complete the course as advised rather than stopping early on your own.
No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.
Common side effects
- Diarrhoea (more common than with amoxicillin alone)
- Nausea
- Vomiting
- Stomach upset
- Thrush
Serious effects — get help
- Signs of a severe allergic reaction such as facial or throat swelling and difficulty breathing
- Yellowing of the skin or eyes or dark urine (possible liver problem, which can sometimes appear days or weeks after stopping)
- Severe, persistent or bloody diarrhoea
- Severe skin reactions such as blistering or peeling
If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.
Interactions to watch
- Blood-thinning medicines such as warfarin
- Methotrexate
- Allopurinol
- Other antibiotics
- Hormonal contraception may be less reliable during vomiting or diarrhoea
Who should take care
- Tell your clinician about any penicillin allergy
- Tell your clinician if you have had liver problems or jaundice with this medicine before
- Tell your clinician if you have kidney problems
- Discuss pregnancy or breastfeeding with your doctor or pharmacist
- Mention glandular fever, which raises the chance of a rash