What it is used for
- Type 2 diabetes (to lower blood sugar when lifestyle measures or metformin alone are not enough)
How it works
Gliclazide encourages the pancreas to release more of its own insulin, which lowers blood sugar. Like other sulfonylureas it can cause blood sugar to fall too low if meals are missed.
How it is taken
Comes as standard tablets and modified-release (slow-release) tablets taken by mouth, usually with a meal. Take it exactly as your doctor, pharmacist, or the label directs; the two forms are not interchangeable.
No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.
Common side effects
- Low blood sugar (hypoglycaemia)
- Stomach upset, nausea, or indigestion
- Weight gain
- Mild skin rash or itching
Serious effects — get help
- Severe low blood sugar with confusion, seizures, or loss of consciousness — seek emergency care
- Serious skin or allergic reaction (blistering, widespread rash, swelling)
- Signs of liver problems such as yellowing skin or eyes
If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.
Interactions to watch
- Other glucose-lowering medicines and insulin
- Alcohol (worsens low blood sugar)
- Some antibiotics, antifungals, and anti-inflammatory medicines
- Certain blood-pressure and steroid medicines that affect blood sugar
Who should take care
- Greater risk of low blood sugar in older adults and people with kidney or liver disease
- Keep meals regular and carry a fast-acting sugar source
- Generally avoided in pregnancy and breastfeeding unless advised by a doctor
- Tell your doctor about any other medicines, including over-the-counter and herbal products