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Antidiabetic / alpha-glucosidase inhibitor

Acarbose: uses, side effects & precautions

Also known as Glucobay, Precose, Prandase.

Esta información es solo orientativa de carácter general y no constituye un consejo médico. Consulta siempre a un profesional sanitario cualificado para cualquier asunto médico personal. En caso de emergencia, llama al número de emergencias de tu zona.

What it is used for

  • Type 2 diabetes (to reduce the rise in blood sugar after meals, often with other treatments)

How it works

Acarbose slows the breakdown and absorption of carbohydrates in the gut, which blunts the spike in blood sugar that normally follows a meal.

How it is taken

Available as tablets taken by mouth, usually with the first bite of a meal. Take it exactly as your doctor, pharmacist, or the label directs; it works best when taken at the start of carbohydrate-containing meals.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Wind (flatulence) and bloating
  • Abdominal discomfort or cramps
  • Diarrhoea
  • Symptoms often ease as the body adjusts

Serious effects — get help

  • Signs of liver problems (yellow skin or eyes, dark urine, persistent nausea) — see your doctor
  • Severe or persistent abdominal pain or bowel symptoms
  • Serious allergic reaction (uncommon)

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Other diabetes medicines and insulin (added low-blood-sugar risk)
  • Some digestive enzyme supplements may reduce its effect
  • Certain medicines for stomach or bowel conditions
  • Check all medicines with your pharmacist

Who should take care

  • If you have low blood sugar while on acarbose plus another diabetes drug, use glucose (not ordinary table sugar), as acarbose slows the breakdown of normal sugar
  • Avoided in some bowel conditions such as inflammatory bowel disease or obstruction
  • Use with caution in liver problems; liver checks may be advised
  • Discuss pregnancy and breastfeeding with your clinician
  • Introduce slowly to reduce gut side effects, as your doctor directs

Frequently asked questions

Why do I need glucose, not sugar, for a low while on acarbose?
Acarbose slows the breakdown of ordinary table sugar, so to treat low blood sugar you should use pure glucose tablets or gel, which are absorbed quickly.
Why does it cause so much wind?
Unabsorbed carbohydrate is fermented in the gut, causing gas and bloating. This often improves over time and with a gradual start.
When should I take it?
With the first bite of a meal, since it works on the carbohydrates you eat. Follow your label exactly.
Does it cause low blood sugar by itself?
On its own it rarely does. The risk rises if combined with insulin or sulfonylureas.
Is Acarbose safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

Related conditions

Related medicines

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