What it is used for
- Cytomegalovirus (CMV) infection in people with weakened immune systems
- CMV eye disease (retinitis)
- Prevention and treatment of CMV around organ or bone-marrow transplantation
How it works
Ganciclovir blocks the enzyme cytomegalovirus uses to copy its DNA, stopping the virus from multiplying. It is reserved for serious CMV infections, particularly in people whose immune systems cannot control the virus on their own.
How it is taken
Usually given as an injection or drip (infusion) into a vein in hospital; an eye implant has also been used for CMV eye disease. It is administered and monitored by specialist healthcare staff, who arrange regular blood tests. There is no routine patient self-administration of the intravenous form.
No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.
Common side effects
- Reduced blood cell counts (tiredness, increased infections, easy bruising)
- Nausea
- Diarrhoea
- Fever
- Headache
Serious effects — get help
- Severe drops in white cells, red cells, or platelets
- Signs of kidney problems
- Seizures or marked confusion
- Severe allergic reaction
- Signs of serious infection due to low blood counts
If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.
Interactions to watch
- Other medicines that lower blood counts or affect the kidneys
- Some antivirals and immunosuppressants used after transplant
- The care team reviews all medicines and adjusts treatment accordingly
Who should take care
- Frequent blood tests monitor blood counts and kidney function
- Effective contraception is usually advised during and for a period after treatment for both men and women
- Handled as a hazardous drug by healthcare staff
- Used in pregnancy only when essential
- Tell the team about any kidney problems