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Topical soothing agent (antipruritic / skin protectant)

Calamine: uses, side effects & precautions

Also known as Calamine lotion, Caladryl.

This information is for general guidance only and does not constitute medical advice. Always consult a qualified healthcare professional for personal medical concerns. In an emergency, call your local emergency number.

What it is used for

  • Itching from insect bites and stings
  • Mild sunburn
  • Chickenpox itch
  • Heat rash and minor skin irritation
  • Itch from poison ivy and similar plant rashes

How it works

Calamine has a mild cooling and soothing effect on the skin that helps relieve itching and irritation, and it can help dry out weeping or oozing rashes.

How it is taken

Usually a lotion or cream applied to the skin. Dab or smooth it onto the affected area as the label directs and let it dry. It is for the surface of the skin only; avoid broken or deeply damaged skin unless advised, and do not use it near the eyes.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Mild dryness of the skin
  • Occasional mild irritation

Serious effects — get help

  • Signs of an allergic reaction such as a worsening rash, swelling or difficulty breathing (uncommon)

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Generally few; avoid layering with other irritating topical products on the same broken skin

Who should take care

  • Avoid the eyes, inside the nose and mouth
  • Seek advice if a rash is severe, spreading, blistering or not improving
  • For children with widespread rashes such as chickenpox, ask a pharmacist about the best soothing options

Frequently asked questions

Does calamine cure the rash?
No. It soothes itching and irritation while the underlying problem settles; it does not treat infections or the cause of a rash.
Can I use it on my child's chickenpox?
It is often used to ease chickenpox itch. Ask a pharmacist about how to apply it and about other comfort measures for children.
Is it safe on sunburn?
It can soothe mild sunburn, but severe sunburn with blistering or feeling unwell needs medical advice.
Why does it leave a chalky layer?
That dried residue is normal and part of how it soothes and dries the skin. You can gently wash it off when reapplying.

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