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Lipid-lowering agent (fibrate)

Fenofibrate: uses, side effects & precautions

Also known as Tricor, Lipantil, Fenofibric acid.

Diese Informationen dienen ausschließlich der allgemeinen Orientierung und stellen keine medizinische Beratung dar. Konsultieren Sie bei persönlichen gesundheitlichen Anliegen stets eine qualifizierte medizinische Fachkraft. Wählen Sie im Notfall Ihre örtliche Notrufnummer.

What it is used for

  • High triglycerides
  • Mixed cholesterol problems where triglycerides are particularly raised
  • Sometimes used with a statin under specialist guidance

How it works

Fenofibrate helps the body break down and clear triglycerides (a type of fat) from the blood and can modestly raise 'good' HDL cholesterol. This lowers very high triglyceride levels that can otherwise harm the pancreas and arteries.

How it is taken

Usually supplied as oral tablets or capsules, generally taken once a day; some forms are taken with food. Take it exactly as your doctor or pharmacist directs and as shown on the label, alongside a healthy diet low in fatty and sugary foods.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Tummy upset, nausea or diarrhoea
  • Headache
  • Muscle aches
  • Back pain
  • Runny or stuffy nose

Serious effects — get help

  • Severe, unexplained muscle pain, tenderness or weakness, especially with fever or dark urine - seek urgent care
  • Signs of gallstones or pancreas problems: severe upper tummy pain, especially spreading to the back
  • Signs of liver problems: yellow skin or eyes, dark urine, severe tiredness
  • Serious allergic or skin reaction: widespread rash, blistering, facial swelling, trouble breathing

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Statins (combined use raises the risk of muscle problems and needs monitoring)
  • Blood thinners such as warfarin (effect can be increased - monitoring needed)
  • Ciclosporin and some other kidney-affecting medicines
  • Certain diabetes medicines

Who should take care

  • Avoid in pregnancy and breastfeeding unless your clinician advises otherwise
  • Tell your clinician about any liver, kidney or gallbladder disease
  • Report any past muscle disorders
  • Mention if you take a statin or a blood thinner
  • Share your full medicine list

Frequently asked questions

Why am I on fenofibrate rather than a statin?
Fibrates are mainly used when triglycerides are very high. Statins are usually first choice for raised LDL cholesterol. Your clinician chooses based on your specific blood results.
Can I take it with my statin?
Sometimes both are used together, but this raises the risk of muscle problems and needs closer monitoring. Only combine them if your clinician has prescribed it that way.
Does it affect my blood thinner?
Fenofibrate can increase the effect of warfarin and similar blood thinners. Your clinician may check your blood-clotting tests more often - mention all your medicines.
Do I still need diet changes?
Yes. Cutting back on alcohol, sugary foods and saturated fat is an important part of lowering triglycerides.
Is Fenofibrate safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

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