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Second-generation (non-drowsy) antihistamine (H1 receptor antagonist)

Loratadine: uses, side effects & precautions

Also known as Claritin, Clarityn, Alavert.

Deze informatie is uitsluitend bedoeld als algemene richtlijn en vormt geen medisch advies. Raadpleeg altijd een gekwalificeerde zorgprofessional voor persoonlijke medische vragen. Bel in geval van nood uw lokale alarmnummer.

What it is used for

  • Hay fever (allergic rhinitis)
  • Sneezing, runny or itchy nose
  • Itchy, watery eyes
  • Hives (urticaria) and itchy skin
  • Other allergy symptoms from pollen, dust, or animals

How it works

Loratadine blocks the action of histamine, a substance the body produces during allergic reactions. This eases symptoms such as sneezing, itching, and a runny nose.

How it is taken

Available as tablets, dissolvable tablets, capsules, and a liquid syrup for children. It is taken by mouth, usually with or without food. Take it exactly as directed by your doctor, pharmacist, or the label, and avoid taking more than recommended.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Headache
  • Drowsiness (uncommon)
  • Tiredness
  • Dry mouth
  • Nervousness or feeling restless (more often in children)
  • Stomach upset

Serious effects — get help

  • Signs of a severe allergic reaction (swelling of face, lips, tongue or throat; difficulty breathing)
  • Fast or pounding heartbeat
  • Yellowing of the skin or eyes (rare liver effects)
  • Seizures (rare)

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Other sedating medicines (may add to any drowsiness)
  • Alcohol
  • Certain medicines that affect liver enzymes (your pharmacist can check)
  • Other antihistamines or combination cold/allergy products

Who should take care

  • Tell your clinician if you are pregnant, planning pregnancy, or breastfeeding
  • Caution with liver problems (dose may need adjusting)
  • Avoid if you are allergic to loratadine or desloratadine
  • Generally non-drowsy, but check how it affects you before driving

Frequently asked questions

Is loratadine non-drowsy?
Yes, it is considered non-drowsy for most people, though a few may still feel mild sleepiness.
How long does loratadine take to work?
It generally starts to ease symptoms within a few hours of taking it.
Can I take loratadine with other allergy medicines?
Avoid combining different antihistamines unless your doctor or pharmacist advises it, to prevent excess side effects.
Can children take loratadine?
There are syrup forms for children, but always follow the label and a pharmacist's or doctor's guidance on suitability and amount.
Is Loratadine safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

Related conditions

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