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Second-generation (non-drowsy) antihistamine (H1 receptor antagonist)

Desloratadine: uses, side effects & precautions

Also known as Aerius, Clarinex, Neoclarityn.

Deze informatie is uitsluitend bedoeld als algemene richtlijn en vormt geen medisch advies. Raadpleeg altijd een gekwalificeerde zorgprofessional voor persoonlijke medische vragen. Bel in geval van nood uw lokale alarmnummer.

What it is used for

  • Hay fever (allergic rhinitis)
  • Sneezing, runny or itchy nose
  • Itchy, watery eyes
  • Chronic hives (urticaria) and itchy skin
  • Allergy symptoms from pollen, dust, or animals

How it works

Desloratadine blocks histamine, the chemical behind allergy symptoms, easing sneezing, itching, and a runny nose. It is the active form of loratadine.

How it is taken

Comes as tablets, dissolvable tablets, and a liquid (often for children). It is taken by mouth, with or without food. Take it exactly as your doctor, pharmacist, or the label directs, and do not exceed the recommended amount.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Headache
  • Tiredness or drowsiness (uncommon)
  • Dry mouth
  • Stomach upset
  • Muscle aches

Serious effects — get help

  • Signs of a severe allergic reaction (swelling, breathing difficulty)
  • Fast or pounding heartbeat
  • Seizures (rare)
  • Yellowing of the skin or eyes (rare liver effects)

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Other sedating medicines (may add to any drowsiness)
  • Alcohol
  • Other antihistamines or combination allergy products

Who should take care

  • Tell your clinician if you are pregnant, planning pregnancy, or breastfeeding
  • Caution with liver or kidney problems
  • Avoid if allergic to desloratadine or loratadine
  • Generally non-drowsy, but check how it affects you before driving

Frequently asked questions

How is desloratadine different from loratadine?
Desloratadine is the active form of loratadine. They work in a very similar way; individual responses vary.
Is desloratadine non-drowsy?
Yes, it is considered non-drowsy for most people, though a few may feel mild tiredness.
How quickly does it work?
It generally begins to ease symptoms within a few hours.
Can children take it?
There are liquid forms for children, but always follow the label and a pharmacist's or doctor's guidance.
Is Desloratadine safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

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