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Antibiotic (lincosamide)

Clindamycin: uses, side effects & precautions

Also known as Cleocin, Dalacin, Clindesse.

Deze informatie is uitsluitend bedoeld als algemene richtlijn en vormt geen medisch advies. Raadpleeg altijd een gekwalificeerde zorgprofessional voor persoonlijke medische vragen. Bel in geval van nood uw lokale alarmnummer.

What it is used for

  • Some skin and soft-tissue infections
  • Dental and bone infections
  • Acne (as a skin treatment)
  • Bacterial vaginosis (as a vaginal cream)
  • Some serious infections, often when other antibiotics are unsuitable
  • An option for some people allergic to penicillin

How it works

Clindamycin is a lincosamide antibiotic. It blocks bacteria from making the proteins they need to grow and multiply. It is effective against several bacteria, including some that grow without oxygen.

How it is taken

Comes as capsules, a liquid, a skin gel, lotion or solution for acne, a vaginal cream, and an injection in hospital. Take or use it exactly as your doctor or pharmacist directs and follow the label. Swallow capsules with a full glass of water. Complete the course as advised.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach upset
  • A metallic taste
  • Skin irritation (with the skin products)

Serious effects — get help

  • Severe, watery or bloody diarrhoea during or after treatment (possible serious bowel infection)
  • Severe allergic reaction with swelling or breathing difficulty
  • Yellowing of the skin or eyes
  • Severe blistering or peeling skin reactions
  • Pain or difficulty swallowing

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Some muscle-relaxant medicines used in surgery
  • Other antibiotics such as erythromycin
  • Blood thinners such as warfarin
  • Certain medicines processed by the liver

Who should take care

  • Clindamycin carries a higher chance of a serious antibiotic-related bowel infection, so report severe diarrhoea promptly
  • Tell your clinician about any bowel disease
  • Take capsules with plenty of water to protect the food pipe
  • Tell your clinician if you have liver or kidney problems
  • Discuss pregnancy or breastfeeding with your doctor or pharmacist

Frequently asked questions

Why is severe diarrhoea a special concern with clindamycin?
It is more likely than some antibiotics to allow a harmful gut bacterium to overgrow, causing severe diarrhoea. Contact your clinician promptly and avoid anti-diarrhoea medicines unless advised.
Can it be used for acne?
Yes, the skin gel or lotion is used for acne, often alongside other treatments. Use it exactly as directed.
Is it an option if I am allergic to penicillin?
It can be an alternative for some penicillin-allergic people, including for certain dental infections. Your clinician will decide what is suitable.
Should I take capsules with water?
Yes, swallow capsules with a full glass of water to help avoid irritation of the food pipe.
Is Clindamycin safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

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