Skip to content

Osmotic laxative

Macrogol: uses, side effects & precautions

Also known as Movicol, MiraLAX, Laxido, PEG 3350, CosmoCol.

Esta información es solo orientativa de carácter general y no constituye un consejo médico. Consulta siempre a un profesional sanitario cualificado para cualquier asunto médico personal. En caso de emergencia, llama al número de emergencias de tu zona.

What it is used for

  • Constipation
  • Faecal impaction (hardened stool that is hard to pass), under guidance
  • Bowel preparation before some procedures (specific high-volume products)

How it works

Macrogol holds water in the bowel so that stools become softer and bulkier and are easier to pass. It is not absorbed and works gently by softening and increasing stool volume.

How it is taken

Comes as a powder in sachets that is dissolved in water, and as ready-made liquids. It is taken by mouth. Take it exactly as the label or your clinician directs, dissolving each dose in the stated amount of water and keeping up your fluid intake.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Bloating and wind
  • Mild stomach cramps
  • Nausea
  • Loose stools if too much is taken

Serious effects — get help

  • Severe diarrhea with dehydration or salt imbalance
  • Severe abdominal pain, swelling, or vomiting (possible blockage)
  • Signs of significant dehydration
  • Allergic reaction (rare)

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • May affect absorption of some other medicines if taken at the same time — separate timing if advised
  • Few major interactions otherwise

Who should take care

  • Avoid if you have a suspected bowel blockage or certain serious bowel conditions
  • Drink enough fluid with it
  • Tell your clinician about heart or kidney problems, especially with high-volume products
  • Discuss pregnancy and breastfeeding with a pharmacist
  • Seek review if constipation persists or you have severe symptoms

Frequently asked questions

How is macrogol different from lactulose?
Both draw water into the bowel, but macrogol often causes less wind for some people. Your pharmacist can help you choose.
How long until it works?
It usually works within one to three days for constipation. Higher amounts used for impaction work faster under guidance.
Can I take it every day?
It can be used regularly under advice, especially for ongoing constipation. Review with a clinician if you need it long-term.
Is it safe in pregnancy?
It is often considered suitable, but confirm with a pharmacist or doctor.

Related conditions

Related medicines

See a doctor online now