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Beta blocker (cardioselective)

Metoprolol: uses, side effects & precautions

Also known as Lopressor, Toprol-XL, Betaloc, Metolar.

This information is for general guidance only and does not constitute medical advice. Always consult a qualified healthcare professional for personal medical concerns. In an emergency, call your local emergency number.

What it is used for

  • High blood pressure (hypertension)
  • Chest pain from angina
  • Some irregular heart rhythms
  • Heart failure (extended-release form)
  • Protecting the heart after a heart attack

How it works

Metoprolol blocks adrenaline-type hormones at the heart, slowing the heart rate and lowering blood pressure. This reduces the heart's workload and oxygen demand, helping with angina and certain rhythm problems.

How it is taken

Available as immediate-release and extended-release tablets, and as an injection given by a healthcare professional. By mouth it is taken once or more daily depending on the form; extended-release tablets should usually be swallowed whole. Take it exactly as your doctor or pharmacist directs and follow the label, and do not stop suddenly.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Tiredness
  • Dizziness
  • Cold hands and feet
  • Slow heartbeat
  • Sleep problems or vivid dreams

Serious effects — get help

  • Very slow heartbeat, fainting, or severe dizziness
  • Worsening breathlessness, wheezing, or new ankle swelling
  • Sudden worsening of chest pain if stopped abruptly
  • Signs of low blood sugar being masked in people with diabetes
  • Severe depression or mood changes

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Heart-rate-slowing calcium channel blockers (verapamil, diltiazem)
  • Other blood pressure medicines
  • Diabetes medicines including insulin (may hide low-blood-sugar signs)
  • Some asthma or COPD treatments
  • Certain antidepressants and other medicines that affect liver enzymes
  • Clonidine (care needed when stopping)

Who should take care

  • Tell your clinician about asthma, COPD, or other breathing problems
  • Use caution in diabetes, as it can mask low-blood-sugar symptoms
  • Do not stop suddenly — taper under medical guidance
  • Discuss pregnancy or breastfeeding with your doctor
  • Do not crush or chew extended-release tablets unless told it is allowed

Frequently asked questions

What is the difference between Lopressor and Toprol-XL?
They are different forms of metoprolol: an immediate-release salt and an extended-release salt taken once daily. They are not directly interchangeable, so use exactly the product your clinician prescribed.
Can I split or crush the tablets?
Extended-release tablets should usually be swallowed whole or only split if the label or your pharmacist says it is allowed. Crushing can release the dose too quickly.
Why must I not stop it suddenly?
Abruptly stopping a beta blocker can cause a rebound rise in heart rate and blood pressure and may trigger chest pain. Any change should be gradual and supervised.
Is it safe with asthma?
Beta blockers can sometimes affect breathing. Tell your clinician about any lung condition before starting.

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