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Long-acting progestogen-releasing intrauterine contraceptive

Levonorgestrel Intrauterine System: uses, side effects & precautions

Also known as Hormonal coil, IUS, Mirena, Kyleena, Jaydess, Liletta, Skyla.

This information is for general guidance only and does not constitute medical advice. Always consult a qualified healthcare professional for personal medical concerns. In an emergency, call your local emergency number.

What it is used for

  • Long-term contraception
  • Heavy menstrual bleeding
  • Protection of the womb lining during certain hormone therapies
  • Period pain and some symptoms of endometriosis (when prescribed)

How it works

A small T-shaped device placed in the womb that releases a small amount of progestogen locally. It thins the womb lining, thickens cervical mucus, and in some cases reduces ovulation.

How it is taken

Fitted into the womb by a trained clinician during a short procedure and left in place for several years depending on the type. You do not need to do anything daily. Follow your clinician's advice on checking the threads and when it must be replaced or removed.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Irregular bleeding or spotting in the first months
  • Lighter periods or no periods over time
  • Cramping after fitting
  • Headache
  • Acne
  • Breast tenderness
  • Small ovarian cysts that usually settle

Serious effects — get help

  • Severe pelvic pain or fever after fitting (possible infection)
  • Signs that the device has moved or been expelled
  • Severe one-sided abdominal pain (possible ectopic pregnancy)
  • Symptoms of perforation of the womb (rare)

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Few medicine interactions because it acts mainly in the womb
  • Still tell your clinician about all your medicines and conditions

Who should take care

  • Tell your clinician about any current pelvic infection, unexplained bleeding, or possible pregnancy before fitting
  • There is a small risk of infection in the weeks after insertion
  • If you cannot feel the threads or have severe pain, seek assessment
  • Does not protect against STIs

Frequently asked questions

How long does it last?
Depending on the type, it can stay in place for several years for contraception, after which it must be replaced or removed.
Will fitting hurt?
Some people feel cramping or discomfort during and shortly after insertion. Ask your clinician about pain relief options.
Is it normal to have no periods?
Yes, many people have much lighter periods or none at all, which is expected and not harmful.
Can it be removed if I want to get pregnant?
Yes. It can be removed at any time by a clinician, and fertility usually returns quickly.
Is Levonorgestrel Intrauterine System safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

Related conditions

Related medicines

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