What it is used for
- Preventing blood clots after a heart attack or stroke
- Preventing clots after a stent procedure
- Reducing clot risk in peripheral artery disease
- Reducing risk in acute coronary syndrome
How it works
Clopidogrel makes platelets (the cells that help blood clot) less sticky, so they are less likely to clump together and form a dangerous clot in narrowed or treated arteries.
How it is taken
Taken by mouth as a tablet, usually once a day with or without food. Take it exactly as your doctor or pharmacist directs and follow the label. Do not stop without medical advice, especially after a stent, as stopping early can lead to a serious clot; tell any dentist or surgeon that you take it before procedures.
No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.
Common side effects
- Easier bruising
- Nosebleeds or bleeding gums
- Longer bleeding from minor cuts
- Diarrhoea or stomach upset
- Rash or itching
Serious effects — get help
- Heavy, unusual, or uncontrolled bleeding
- Black or bloody stools, or vomiting blood or material that looks like coffee grounds
- Coughing up blood or blood in the urine
- Signs of a rare but serious blood disorder such as unusual bruising, fever, weakness, or yellowing of the skin
- Signs of a serious allergic reaction
If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.
Interactions to watch
- Other blood thinners and antiplatelets such as warfarin, aspirin, or DOACs (higher bleeding risk)
- Some stomach-acid medicines such as omeprazole and esomeprazole (may reduce effect)
- Non-steroidal anti-inflammatory drugs such as ibuprofen
- Certain antidepressants (SSRIs/SNRIs)
- Some antifungal medicines
Who should take care
- Tell every clinician, dentist, and surgeon that you take it before any procedure
- Tell your clinician about stomach ulcers or recent bleeding
- Do not stop suddenly after a stent without medical advice
- Discuss pregnancy or breastfeeding with your doctor
- Report any unusual or prolonged bleeding