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Anti-inflammatory / local analgesic (oromucosal)

Benzydamine: uses, side effects & precautions

Also known as Difflam, Tantum Verde, Difflam-C.

This information is for general guidance only and does not constitute medical advice. Always consult a qualified healthcare professional for personal medical concerns. In an emergency, call your local emergency number.

What it is used for

  • Painful mouth and throat conditions
  • Sore throat
  • Mouth ulcers and mouth soreness
  • Mouth pain after dental procedures or from radiotherapy (under supervision)

How it works

Benzydamine reduces inflammation and numbs the surface of the mouth and throat where it is applied, easing pain and soreness. It works locally on the lining of the mouth and throat rather than being absorbed for a whole-body effect.

How it is taken

Comes as a mouthwash/gargle and a throat spray. The mouthwash is swished or gargled and then spat out, and the spray is aimed at the sore area. Some people dilute the mouthwash if it stings, as directed. Use it exactly as your doctor, pharmacist or the label directs. It is for use in the mouth and throat only, not for swallowing in large amounts.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Numbness or tingling in the mouth
  • Stinging on application (can be eased by diluting the mouthwash if directed)
  • Dry mouth
  • An unusual taste

Serious effects — get help

  • Signs of an allergic reaction such as facial or throat swelling, severe rash or difficulty breathing
  • Worsening sore throat with high fever, or difficulty swallowing or breathing (which need urgent assessment)

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Generally few, as little is absorbed
  • Other mouth/throat products (ask a pharmacist about combining)

Who should take care

  • Spit out the mouthwash rather than swallowing it
  • See a clinician if a sore throat is severe, persists, or comes with high fever or difficulty swallowing
  • Tell a pharmacist if you are pregnant or breastfeeding
  • Not usually recommended for young children unless advised

Frequently asked questions

It stings when I use the mouthwash. What can I do?
Some people are advised to dilute it with water to reduce stinging. Follow the label or ask your pharmacist.
Should I swallow the mouthwash?
No. Swish or gargle and then spit it out unless your clinician specifically tells you otherwise.
When should I see a doctor for a sore throat?
Seek care for a severe or persistent sore throat, high fever, difficulty swallowing or breathing, or a rash, as these may need different treatment.
Can children use it?
Some products have age limits. Check the label and ask a pharmacist before giving it to a child.
Is Benzydamine safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

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