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Antipsychotic (atypical / second-generation)

Risperidone: uses, side effects & precautions

Also known as Risperdal.

Diese Informationen dienen ausschließlich der allgemeinen Orientierung und stellen keine medizinische Beratung dar. Konsultieren Sie bei persönlichen gesundheitlichen Anliegen stets eine qualifizierte medizinische Fachkraft. Wählen Sie im Notfall Ihre örtliche Notrufnummer.

What it is used for

  • Schizophrenia
  • Bipolar disorder (mania)
  • Short-term treatment of persistent severe aggression in certain conditions (specialist use)

How it works

Risperidone acts mainly on dopamine and serotonin signalling in the brain, helping to rebalance the chemical messengers involved in perception, thinking and mood.

How it is taken

Usually available as tablets, orodispersible tablets, an oral liquid and a long-acting injection given by a healthcare professional. The oral form is taken by mouth. Take it exactly as your doctor or pharmacist directs and follow the label; do not stop suddenly.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Drowsiness
  • Dizziness
  • Weight gain
  • Increased appetite
  • Restlessness
  • Tremor or stiffness
  • Constipation
  • Increased saliva
  • Headache

Serious effects — get help

  • Movement problems: tremor, stiffness, restlessness, or uncontrolled movements that may persist
  • Neuroleptic malignant syndrome: high fever, severe muscle stiffness, confusion (medical emergency)
  • Signs of high blood sugar
  • Raised prolactin: breast changes, milk production, menstrual changes, sexual difficulties
  • Irregular heartbeat or fainting
  • Signs of low white blood cells: fever, sore throat, infections
  • New or worsening suicidal thoughts

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Alcohol and other sedating medicines (added drowsiness)
  • Medicines that affect heart rhythm
  • Some medicines that change how the liver processes it
  • Blood-pressure and Parkinson's-disease medicines

Who should take care

  • More likely than some others to cause movement-related effects and raised prolactin
  • Use with caution with heart conditions, diabetes, seizures, Parkinson's disease or in older adults with dementia (higher risks)
  • May cause dizziness on standing; rise slowly
  • Tell your clinician if you are pregnant, planning pregnancy or breastfeeding
  • Do not stop suddenly; taper under medical guidance

Frequently asked questions

Why might I feel stiff or restless on risperidone?
It can cause movement-related effects such as stiffness, tremor or an inability to sit still, particularly at higher amounts. Tell your clinician, as the amount can be adjusted or other medicines added to help.
What is raised prolactin and why does it matter?
Risperidone can raise a hormone called prolactin, which may cause breast tenderness or milk production, menstrual changes or sexual difficulties. Report these so your clinician can review your treatment.
What is the long-acting injection?
A long-acting injection given by a healthcare professional releases the medicine slowly over weeks, which can help people who prefer not to take daily tablets.
Can older adults with dementia take it?
Antipsychotics carry higher risks in older adults with dementia and are used only with great caution for specific reasons. A specialist weighs the risks and benefits carefully.
Is Risperidone safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

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