What it is used for
- Preventing clots after a heart attack or acute coronary syndrome treated with a stent
- Used together with low-dose aspirin for a set period after a stent
- Reducing the risk of further heart attacks in selected people
How it works
Prasugrel stops platelets from clumping by blocking the P2Y12 receptor they use to stick together. This reduces the chance of a clot forming on a stent or in a narrowed heart artery.
How it is taken
Usually supplied as oral tablets, generally taken once a day with or without food, typically alongside low-dose aspirin. Take it exactly as your doctor or pharmacist directs and do not stop early after a stent without specialist advice.
No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.
Common side effects
- Easy bruising
- Nosebleeds or bleeding gums
- Minor bleeding from cuts that takes longer to stop
- Headache
- Dizziness
Serious effects — get help
- Heavy or uncontrolled bleeding, black/tarry stools, blood in urine, vomiting or coughing up blood - seek urgent care
- Sudden severe headache, weakness or confusion (possible brain bleed) - emergency
- A rare but serious blood disorder (TTP): unexplained bruising, tiny red skin spots, extreme tiredness, fever, confusion - seek urgent care
- Serious allergic reaction: facial or throat swelling, trouble breathing
If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.
Interactions to watch
- Other blood thinners and antiplatelets including warfarin and aspirin
- Anti-inflammatory painkillers (NSAIDs)
- Some antidepressants (SSRIs)
- Alcohol in excess
Who should take care
- Generally not suitable for people who have had a stroke or 'mini-stroke', or for the very elderly or very low body weight without special caution - your clinician will assess this
- Tell any doctor, dentist or surgeon you take it before procedures
- Do not stop early after a stent without specialist advice
- Report any bleeding disorders or liver problems
- Discuss pregnancy or breastfeeding with your clinician