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Antidiabetic / GLP-1 receptor agonist

Liraglutide: uses, side effects & precautions

Also known as Victoza, Saxenda.

Deze informatie is uitsluitend bedoeld als algemene richtlijn en vormt geen medisch advies. Raadpleeg altijd een gekwalificeerde zorgprofessional voor persoonlijke medische vragen. Bel in geval van nood uw lokale alarmnummer.

What it is used for

  • Type 2 diabetes (to improve blood sugar control)
  • Weight management in certain people (under a different brand and on a doctor's advice)

How it works

Liraglutide mimics a natural gut hormone (GLP-1) that prompts the body to release insulin after meals, reduces sugar made by the liver, slows stomach emptying, and reduces appetite, helping lower blood sugar and support weight control.

How it is taken

Given as an injection under the skin using a pre-filled pen, usually once a day. Use it exactly as your doctor or diabetes nurse shows you and as the label directs; rotate injection sites and never share pens or needles.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Nausea, especially when starting
  • Vomiting or diarrhoea
  • Reduced appetite
  • Constipation
  • Injection-site reactions

Serious effects — get help

  • Severe, persistent stomach pain possibly spreading to the back (possible pancreatitis) — seek urgent care
  • Gallbladder problems (pain in the upper right abdomen, fever, yellowing skin) — seek medical care
  • Signs of a serious allergic reaction
  • A lump or swelling in the neck, trouble swallowing, or persistent hoarseness (rare thyroid concern) — tell your doctor

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Insulin and sulfonylureas (added low-blood-sugar risk)
  • Because it slows stomach emptying, it can affect the absorption of some oral medicines
  • Alcohol (can affect blood sugar)
  • Check all medicines with your pharmacist

Who should take care

  • Tell your doctor about any history of pancreatitis or certain thyroid cancers (medullary thyroid cancer / MEN 2)
  • Start-up nausea often eases over time; report severe or persistent vomiting
  • Stay hydrated if you have vomiting or diarrhoea
  • Generally avoided in pregnancy and breastfeeding unless advised
  • Report severe abdominal pain promptly

Frequently asked questions

Will liraglutide help me lose weight?
It can reduce appetite and support weight loss; a separate brand is licensed specifically for weight management. Any use should be guided by your doctor.
Why does it make me feel sick at first?
Nausea is common when starting and usually settles over a few weeks. Eating smaller meals can help; tell your doctor if it is severe or persistent.
Does it cause low blood sugar?
On its own it rarely does, but the risk rises if combined with insulin or a sulfonylurea.
Is it the same as the weekly injections?
Liraglutide is usually taken daily. Some other GLP-1 medicines are taken weekly. Your doctor chooses based on your needs.
Is Liraglutide safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

Related conditions

Related medicines

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