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Antidepressant (SSRI - selective serotonin reuptake inhibitor)

Citalopram: uses, side effects & precautions

Also known as Celexa, Cipramil.

Deze informatie is uitsluitend bedoeld als algemene richtlijn en vormt geen medisch advies. Raadpleeg altijd een gekwalificeerde zorgprofessional voor persoonlijke medische vragen. Bel in geval van nood uw lokale alarmnummer.

What it is used for

  • Depression
  • Panic disorder
  • Anxiety disorders

How it works

Citalopram increases the availability of serotonin in the brain by slowing its reabsorption into nerve cells, which is thought to help improve mood and reduce anxiety over several weeks.

How it is taken

Usually available as tablets and as oral drops/liquid. It is taken by mouth, normally once a day. Take it exactly as directed by your doctor or pharmacist and follow the label; the daily amount may be limited because of effects on heart rhythm, so do not exceed what is prescribed.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Nausea
  • Dry mouth
  • Drowsiness or trouble sleeping
  • Sweating
  • Headache
  • Dizziness
  • Reduced appetite
  • Sexual difficulties
  • Tiredness

Serious effects — get help

  • New or worsening suicidal thoughts, especially early on (seek urgent help)
  • Irregular or fast heartbeat, fainting (possible heart-rhythm effect)
  • Serotonin syndrome: agitation, fever, muscle twitching, confusion
  • Severe allergic reaction
  • Unusual bleeding
  • Seizures
  • Signs of low sodium: confusion, weakness

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • MAOI antidepressants (must not be combined)
  • Medicines that affect heart rhythm / prolong the QT interval
  • Other serotonin-raising medicines (triptans, tramadol, St John's Wort)
  • Blood thinners, aspirin and NSAIDs (bleeding risk)
  • Alcohol
  • Some antifungal and antibiotic medicines

Who should take care

  • Citalopram can affect heart rhythm, so dose limits apply and caution is needed with heart conditions
  • Tell your clinician if you are pregnant, planning pregnancy or breastfeeding
  • Use with caution with liver or kidney problems, epilepsy or low potassium/magnesium
  • Closer monitoring may be needed for people under 25
  • Do not stop suddenly; taper under medical guidance

Frequently asked questions

Why is there a maximum dose for citalopram?
At higher amounts citalopram can affect the heart's electrical rhythm (QT interval). For safety, prescribers keep within recommended limits, which can be lower for older adults or people with certain conditions.
How is citalopram different from escitalopram?
Escitalopram is a refined version of citalopram. They are closely related; your clinician chooses based on your needs and response. Do not take both together.
How long until it works?
Full benefit usually takes 4-6 weeks. Keep taking it as prescribed and review with your clinician.
Can I drink alcohol?
Alcohol can add to drowsiness and may worsen mood symptoms. Ask your clinician or pharmacist about your situation.
Is Citalopram safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

Related conditions

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