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Antibiotic (topical, for eyes/ears)

Chloramphenicol: uses, side effects & precautions

Also known as Optrex Infected Eyes, Golden Eye Antibiotic, Brochlor, Chloromycetin, Optichlor.

Deze informatie is uitsluitend bedoeld als algemene richtlijn en vormt geen medisch advies. Raadpleeg altijd een gekwalificeerde zorgprofessional voor persoonlijke medische vragen. Bel in geval van nood uw lokale alarmnummer.

What it is used for

  • Bacterial conjunctivitis ('pink eye' caused by bacteria)
  • Bacterial eye infections
  • Some bacterial ear infections
  • Eye infections after minor injury or foreign body removal

How it works

Chloramphenicol is an antibiotic that stops bacteria from making the proteins they need to grow and multiply. Applied directly to the eye or ear, it tackles the infection where it is, with very little entering the rest of the body.

How it is taken

Comes as eye drops and an eye ointment, and sometimes as ear drops. Drops are placed into the affected eye or ear and ointment is applied along the inside of the lower eyelid. Wash your hands first, avoid touching the dropper tip to your eye, skin or any surface, and complete the full course even if symptoms improve. Use it exactly as your doctor, pharmacist or the package label directs, and do not share the bottle with anyone else.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Brief stinging, burning or itching when applied
  • Temporary blurred vision (with ointment)
  • Watery eyes
  • Mild eye irritation or redness

Serious effects — get help

  • Signs of an allergic reaction such as facial swelling, a widespread rash, or difficulty breathing
  • Worsening eye pain, swelling or vision changes despite treatment
  • Very rarely, serious blood disorders linked to chloramphenicol (seek urgent care for unexplained bruising, bleeding, sore throat or fever)

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Other eye drops or ointments (space applications apart and ask a pharmacist)
  • Contact lenses (generally avoid wearing while treating an eye infection)
  • Tell your clinician about all medicines if chloramphenicol is ever used in any non-topical form

Who should take care

  • Tell your clinician if you are pregnant or breastfeeding
  • Mention any history of blood disorders or bone marrow problems
  • Not suitable if you are allergic to chloramphenicol
  • Use with caution in very young infants only under medical advice
  • Discard the bottle after the period your pharmacist or label specifies once opened

Frequently asked questions

How will I know if my eye infection is getting better?
Redness, discharge and discomfort usually start to ease within a couple of days. If there is no improvement, or things get worse, contact your doctor or pharmacist rather than continuing on your own.
Can I wear contact lenses while using chloramphenicol eye drops?
It is generally best to stop wearing lenses during an eye infection and while you are treating it. Ask your eye-care professional when it is safe to start again.
Why does my vision blur after the ointment?
Eye ointments can briefly cloud vision. Do not drive or operate machinery until your sight clears. Many people use ointment at bedtime for this reason, but follow your label.
Can I use the same bottle for a future infection?
No. Once opened, eye and ear drops should be discarded after the time your pharmacist or label states, and you should not reuse or share them, to avoid spreading infection.
Is Chloramphenicol safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

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