What it is used for
- High cholesterol (raised LDL)
- Reducing the risk of heart attack and stroke in people at risk
- Slowing the build-up of fatty plaque in the arteries
How it works
Pravastatin blocks the liver enzyme that makes cholesterol, so the liver removes more LDL cholesterol from the blood. This lowers cholesterol levels and helps protect the heart and blood vessels.
How it is taken
Usually supplied as oral tablets, generally taken once a day with or without food, often in the evening. Take it exactly as directed by your doctor or pharmacist and as shown on the label, along with a healthy diet.
No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.
Common side effects
- Muscle aches
- Headache
- Nausea or stomach upset
- Diarrhoea
- Cold-like symptoms
- Tiredness
Serious effects — get help
- Severe, unexplained muscle pain, tenderness or weakness, especially with fever or dark urine - seek urgent care
- Signs of liver problems: yellow skin or eyes, dark urine, severe abdominal pain, unusual tiredness
- Serious allergic reaction: facial or throat swelling, difficulty breathing, severe rash
If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.
Interactions to watch
- Other lipid-lowering drugs such as fibrates and niacin
- Ciclosporin
- Certain antibiotics
- Some bile-acid binding medicines (may need spacing apart)
- Heavy alcohol use
Who should take care
- Avoid in pregnancy and breastfeeding unless your clinician advises otherwise
- Report any liver disease or heavy alcohol use
- Mention kidney problems or an underactive thyroid
- Tell your clinician about any history of muscle disorders
- Share your full medicine and supplement list