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Topical antiparasitic (scabicide / pediculicide)

Permethrin: uses, side effects & precautions

Also known as Lyclear, Nix, Elimite, Acticin.

Ces informations sont fournies à titre indicatif uniquement et ne constituent pas un avis médical. Consultez toujours un professionnel de santé qualifié pour toute préoccupation médicale personnelle. En cas d'urgence, appelez votre numéro d'urgence local.

What it is used for

  • Scabies (a mite infestation of the skin)
  • Head lice (some products)
  • Other parasitic skin infestations

How it works

Permethrin paralyses and kills the mites or lice and their eggs on contact by disrupting their nervous system. Applied to the skin or scalp, it clears the infestation while being poorly absorbed into the body.

How it is taken

Comes as a cream, lotion or creme rinse. For scabies, it is usually applied over the whole body and left on for a set time before washing off; for head lice it is applied to the hair and scalp. Wash your hands after applying (unless treating the hands). Use it exactly as your doctor, pharmacist or the label directs, and treat close contacts and wash bedding and clothing as advised to prevent reinfestation.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Itching, which can briefly worsen after treatment
  • Mild stinging, burning or tingling
  • Redness or mild skin irritation
  • Temporary numbness or rash at the site

Serious effects — get help

  • Signs of a severe allergic reaction such as facial swelling, widespread rash or difficulty breathing
  • Severe skin irritation, blistering or swelling
  • Worsening or spreading infection of the skin

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Other skin products on the same area (ask a pharmacist)
  • Generally few interactions because little is absorbed

Who should take care

  • Tell your clinician if you are pregnant or breastfeeding
  • Take care around the eyes, mouth and broken skin
  • Treat household and close contacts at the same time to prevent reinfestation
  • Itching can persist for a while after successful treatment and does not always mean failure
  • Use the correct product and method for scabies versus head lice

Frequently asked questions

Why do I still itch after treatment?
Itching from scabies can continue for some time even after the mites are gone, as the skin reacts. Persistent or worsening itch should be checked with a clinician.
Do I need to treat my family too?
For scabies, close contacts are usually treated at the same time, even without symptoms, to prevent reinfestation. Follow your clinician's advice.
How should I treat bedding and clothes?
Wash and hot-dry clothing, bedding and towels, or seal them away as advised, to remove mites and prevent reinfestation.
Can I use it on my face?
Follow the instructions carefully; for scabies, application areas are specific. Avoid the eyes and mouth and ask a pharmacist if unsure.
Is Permethrin safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

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