What it is used for
- Chronic hepatitis B infection
- Reducing liver damage and complications from long-term hepatitis B
How it works
Entecavir blocks the enzyme hepatitis B uses to copy its DNA, strongly lowering the amount of virus in the blood. This reduces inflammation and slows liver damage over time. It controls the infection rather than curing it, so it is usually taken long term.
How it is taken
Available as tablets and an oral liquid/solution. It is usually taken on an empty stomach, away from meals, at the same time each day. Take it exactly as your specialist directs, do not stop without advice because hepatitis B can flare up, and attend the blood tests your clinician arranges.
No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.
Common side effects
- Headache
- Tiredness
- Dizziness
- Nausea
Serious effects — get help
- A severe flare-up of hepatitis B if treatment is stopped suddenly
- Signs of lactic acidosis or liver problems (deep rapid breathing, severe tiredness, yellow skin or eyes)
- Signs of kidney problems
- Severe allergic reaction
If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.
Interactions to watch
- Other medicines that affect the kidneys
- Tell your specialist about every medicine, supplement, and herbal product you take
Who should take care
- Take on an empty stomach, away from food, as advised
- Do not stop suddenly, as hepatitis B can rebound severely
- Tell your doctor about kidney problems, as the dose may need adjusting
- HIV status is usually checked first, as entecavir alone is not suitable for people with untreated HIV
- Use in pregnancy or breastfeeding only under specialist guidance