What it is used for
- Reducing stroke risk in people with atrial fibrillation
- Treating and preventing blood clots in the legs (DVT) and lungs (PE)
How it works
Edoxaban blocks factor Xa, an important step in clot formation, making the blood less likely to form harmful clots. It is taken once a day and usually does not need routine clotting tests.
How it is taken
Usually supplied as oral tablets, typically taken once a day with or without food. Take it exactly as your doctor or pharmacist directs and as written on the label, and do not stop suddenly without advice, as clot risk can rise.
No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.
Common side effects
- Easy bruising
- Nosebleeds or bleeding gums
- Heavier periods
- Mild tummy upset
- Rash
Serious effects — get help
- Heavy or uncontrolled bleeding, black/tarry stools, blood in urine, vomiting or coughing up blood - seek urgent care
- Sudden severe headache, weakness or confusion (possible brain bleed) - emergency
- Serious fall or head injury while taking it - get checked
- Serious allergic reaction: facial or throat swelling, trouble breathing
If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.
Interactions to watch
- Other blood thinners and aspirin
- Anti-inflammatory painkillers (NSAIDs)
- Certain heart-rhythm medicines and some antifungals
- Rifampicin and St John's Wort
- Alcohol in excess
Who should take care
- Generally avoided in pregnancy and breastfeeding - tell your clinician
- Kidney function affects how the medicine works, so it may not suit everyone - your clinician will assess this
- Tell any doctor, dentist or surgeon that you take it before procedures
- Do not stop abruptly without advice
- Carry an anticoagulant alert card if given one