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Aldosterone antagonist with anti-androgen effects (also a diuretic)

Spironolactone: uses, side effects & precautions

Also known as Aldactone, spironolactone, CaroSpir.

Esta información es solo orientativa de carácter general y no constituye un consejo médico. Consulta siempre a un profesional sanitario cualificado para cualquier asunto médico personal. En caso de emergencia, llama al número de emergencias de tu zona.

What it is used for

  • Hormonal acne in women (when prescribed off the usual diuretic use)
  • Excess facial or body hair (hirsutism) related to PCOS
  • It is also used for heart failure, high blood pressure, and fluid retention, covered under those areas

How it works

It blocks the effect of androgen (male-type) hormones on the skin and hair follicles, which can reduce hormonal acne and unwanted hair growth. It also acts as a water tablet.

How it is taken

Taken as a tablet, usually once or twice a day. Take it exactly as your doctor or pharmacist directs, and attend any blood tests they arrange to check your kidney function and potassium.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Increased urination
  • Dizziness or low blood pressure
  • Breast tenderness
  • Irregular periods
  • Tiredness
  • Headache

Serious effects — get help

  • Signs of high potassium (muscle weakness, irregular or slow heartbeat)
  • Severe dizziness or fainting
  • Signs of dehydration
  • Signs of a serious allergic reaction

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Potassium supplements and potassium-rich salt substitutes
  • Some blood pressure medicines (ACE inhibitors, ARBs)
  • NSAIDs
  • Other diuretics
  • Some heart and lithium medicines

Who should take care

  • Reliable contraception is usually advised because it can affect a developing baby, so it is not used in pregnancy
  • Tell your clinician about kidney problems or high potassium
  • Avoid potassium supplements and salt substitutes unless advised
  • Blood tests are used to monitor kidney function and potassium

Frequently asked questions

Why is a water tablet used for acne?
Besides being a diuretic, it blocks androgen hormones that drive hormonal acne and excess hair growth in some women.
How long until my skin improves?
It often takes several weeks to a few months to see the benefit, so consistency matters.
Do I need contraception with it?
Yes, effective contraception is usually advised because it can harm a developing baby.
Should I watch my diet?
Avoid potassium supplements and salt substitutes unless your clinician says otherwise, as it can raise potassium.
Is Spironolactone safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

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