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Second-generation (non-drowsy) antihistamine (H1 receptor antagonist)

Levocetirizine: uses, side effects & precautions

Also known as Xyzal, Xusal.

Esta información es solo orientativa de carácter general y no constituye un consejo médico. Consulta siempre a un profesional sanitario cualificado para cualquier asunto médico personal. En caso de emergencia, llama al número de emergencias de tu zona.

What it is used for

  • Hay fever (allergic rhinitis)
  • Sneezing, runny or itchy nose
  • Itchy, watery eyes
  • Chronic hives (urticaria) and itchy skin
  • Allergy symptoms from pollen, dust, or animals

How it works

Levocetirizine blocks histamine, the chemical that drives allergy symptoms, reducing sneezing, itching, watering, and swelling. It is a refined form of cetirizine.

How it is taken

Comes as tablets and a liquid (often for children). It is taken by mouth, with or without food, often in the evening. Take it exactly as your doctor, pharmacist, or the label directs, and do not exceed the recommended amount.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Drowsiness or tiredness (uncommon but possible)
  • Dry mouth
  • Headache
  • Sore throat or stuffy nose
  • Stomach upset

Serious effects — get help

  • Signs of a severe allergic reaction (swelling, breathing difficulty)
  • Fast or irregular heartbeat
  • Difficulty passing urine
  • Severe restlessness or agitation

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Alcohol (may increase drowsiness)
  • Other sedating medicines
  • Other antihistamines or combination allergy products

Who should take care

  • Tell your clinician if you are pregnant, planning pregnancy, or breastfeeding
  • Caution with kidney problems (dose may need adjusting)
  • Avoid if allergic to levocetirizine, cetirizine, or hydroxyzine
  • It can cause drowsiness in some people — see how it affects you before driving

Frequently asked questions

How is levocetirizine different from cetirizine?
Levocetirizine is the active part of cetirizine. They work very similarly; some people prefer one over the other.
Will it make me sleepy?
It is classed as non-drowsy, but a minority of people feel mild drowsiness. Check how it affects you before driving.
Can I take it every day in allergy season?
Many people do. For long-term use, check with your doctor or pharmacist.
Can I drink alcohol with it?
Alcohol may add to any drowsiness, so it is best limited until you know how the medicine affects you.
Is Levocetirizine safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

Related conditions

Related medicines

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