NSAIDs such as ibuprofen and naproxen reduce pain and inflammation and are widely used for arthritis, sprains, and back pain. However, taken regularly or in higher amounts over long periods, they can increase the risk of stomach ulcers and bleeding, kidney problems, raised blood pressure, and heart problems. The risks are greater in older adults, people with existing kidney, heart, or stomach conditions, and those taking certain other medicines such as blood thinners.
For this reason, the general principle is to use the smallest amount that controls symptoms for the shortest time needed. Some people are advised to take stomach-protecting medicine alongside an NSAID, or to use topical anti-inflammatory gels, which carry lower whole-body risk. Paracetamol is sometimes preferred as a first step depending on the situation.
If you find you need anti-inflammatory painkillers regularly for ongoing joint pain, see a doctor to review the cause and the safest long-term plan, and check with a pharmacist before combining medicines. Do not exceed the doses on the packaging.