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Antispasmodic (smooth-muscle relaxant)

Mebeverine: uses, side effects & precautions

Also known as Colofac, Duspatalin.

Diese Informationen dienen ausschließlich der allgemeinen Orientierung und stellen keine medizinische Beratung dar. Konsultieren Sie bei persönlichen gesundheitlichen Anliegen stets eine qualifizierte medizinische Fachkraft. Wählen Sie im Notfall Ihre örtliche Notrufnummer.

What it is used for

  • Cramping and spasm of irritable bowel syndrome (IBS)
  • Other gut spasm and colicky abdominal pain

How it works

Mebeverine relaxes the muscle in the wall of the gut directly, easing the spasms that cause cramping pain and discomfort, without strongly affecting normal gut movement.

How it is taken

Comes as tablets and modified-release capsules, and sometimes a liquid. It is taken by mouth, often before meals. Take it exactly as the label or your clinician directs; swallow modified-release forms whole.

No doses here on purpose. The right strength and schedule depend on you — only a doctor or pharmacist should set them. Always follow your prescription and the label.

Common side effects

  • Generally well tolerated
  • Occasional indigestion
  • Headache
  • Dizziness

Serious effects — get help

  • Severe allergic reaction (swelling of the face or throat, rash, trouble breathing)
  • Severe or persistent abdominal pain that should be assessed

If a reaction is severe — for example trouble breathing, swelling of the face or throat, or collapse — go to the nearest emergency room now or call your local emergency number. Do not wait for an online consultation.

Interactions to watch

  • Few significant interactions; still tell your pharmacist about all your medicines

Who should take care

  • Avoid if you have a rare bowel-paralysis condition (paralytic ileus)
  • Discuss pregnancy and breastfeeding with a pharmacist
  • New, severe, or changing abdominal symptoms should be assessed by a clinician before assuming it is IBS
  • Swallow modified-release capsules whole

Frequently asked questions

Is mebeverine an antispasmodic only for IBS?
It is mainly used for IBS-type cramps and similar gut spasm. It does not treat constipation or diarrhea directly.
When should I take it?
Often before meals. Follow the exact timing on your label.
Does it cause drowsiness?
It usually does not cause much drowsiness, but tell your pharmacist if you feel dizzy.
Can I take it long-term?
It can be used over longer periods for IBS under guidance. Review with a clinician if symptoms change.
Is Mebeverine safe to take?
For most people it is safe when taken exactly as a doctor or pharmacist advises and as printed on the label. Tell your clinician about your other medicines and health conditions, and seek urgent care for any serious reaction.

Related conditions

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